"P values and accompanying methods of statistical significance testing are creating challenges in biomedical science and other disciplines. [...] P values are misinterpreted, overtrusted, and misused. [...] methodologists recently proposed a specific, simple move: lowering the routine P value threshold for claiming statistical significance from .05 to .005 for new discoveries."
Ioannidis JPA. JAMA. 2018 Mar 22. doi: 10.1001/jama.2018.1536.